Keto Pepperoni Pizza Chicken Bake

Featured in: International BBQ Flavors

Transform simple chicken breasts into a cheesy, satisfying meal that captures all the flavors of your favorite takeout without the carb-heavy crust. Start by searing seasoned chicken to lock in juices, then layer with sugar-free marinara sauce, generous shredded mozzarella, and crispy pepperoni slices. After 20 minutes in the oven, the cheese turns golden and bubbly while the chicken stays tender and moist. Each serving delivers 42g of protein with just 5g net carbs, making it perfect for weeknight dinners or meal prep. Customize with your favorite toppings like sautéed vegetables or fresh herbs.

Updated on Wed, 11 Feb 2026 15:16:29 GMT
Freshly baked Keto Pepperoni Pizza Chicken Bake with melted mozzarella and bubbly golden cheese topping. Save
Freshly baked Keto Pepperoni Pizza Chicken Bake with melted mozzarella and bubbly golden cheese topping. | bitegrill.com

Indulge in all the savory goodness of a classic pepperoni pizza without the carb-heavy crust. This Keto Pepperoni Pizza Chicken Bake transforms simple chicken breasts into a melty, gooey masterpiece layered with rich marinara, mozzarella cheese, and spicy pepperoni. It is the perfect easy weeknight dinner for anyone following a low-carb or gluten-free lifestyle, providing all the comfort of your favorite pizzeria order in a high-protein, satisfying casserole.

Freshly baked Keto Pepperoni Pizza Chicken Bake with melted mozzarella and bubbly golden cheese topping. Save
Freshly baked Keto Pepperoni Pizza Chicken Bake with melted mozzarella and bubbly golden cheese topping. | bitegrill.com

One of the best things about this dish is how it simplifies meal prep. By searing the chicken first, you ensure a juicy texture that stands up to the rich toppings. This bake is a reliable go-to when you need a hearty meal that doesn't require hours in the kitchen, making it a staple for busy weeknights.

Ingredients

  • 4 boneless, skinless chicken breasts (about 1.5 lbs / 680 g)
  • 1 tbsp olive oil
  • 1/2 tsp salt
  • 1/4 tsp black pepper
  • 3/4 cup (180 ml) sugar-free marinara sauce
  • 1 1/2 cups (170 g) shredded mozzarella cheese
  • 20 slices pepperoni (about 60 g)
  • 1/2 tsp dried Italian seasoning
  • 1/4 tsp crushed red pepper flakes (optional)
  • 2 tbsp grated Parmesan cheese
  • 2 tbsp chopped fresh basil or parsley (optional garnish)
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Instructions

Step 1
Preheat oven to 400°F (200°C). Lightly grease a 9x13-inch (23x33 cm) baking dish.
Step 2
Pat chicken breasts dry and season both sides with salt and pepper.
Step 3
Heat olive oil in a large skillet over medium-high heat. Sear chicken breasts for 2–3 minutes per side until lightly golden (they do not need to be cooked through).
Step 4
Arrange the seared chicken breasts in the prepared baking dish.
Step 5
Spoon the marinara sauce evenly over the chicken.
Step 6
Sprinkle mozzarella cheese over the sauce-covered chicken.
Step 7
Layer pepperoni slices over the cheese.
Step 8
Sprinkle with Italian seasoning, red pepper flakes (if using), and Parmesan cheese.
Step 9
Bake uncovered for 20–25 minutes, until the chicken is cooked through (internal temp 165°F/74°C) and cheese is bubbly and golden.
Step 10
Let rest for 5 minutes, garnish with fresh basil or parsley if desired, and serve hot.

Zusatztipps für die Zubereitung

Always use a meat thermometer to ensure the chicken reaches exactly 165°F (74°C). This prevents the meat from becoming dry. Patting the chicken dry before searing is crucial for achieving that golden-brown exterior that adds extra flavor to the final bake.

Varianten und Anpassungen

You can easily modify this recipe to suit your preferences. Use chicken thighs for a juicier variation, or swap the pepperoni for turkey pepperoni to lower the fat content. For extra nutrients and texture, feel free to add sautéed mushrooms, sliced bell peppers, or black olives before adding the cheese.

Serviervorschläge

To make this a complete meal, serve the chicken bake alongside a crisp green side salad with a simple vinaigrette. It also pairs perfectly with steamed broccoli or roasted zucchini to soak up the delicious marinara and melted cheese.

Keto Pepperoni Pizza Chicken Bake with pepperoni slices on a bed of rich marinara sauce. Save
Keto Pepperoni Pizza Chicken Bake with pepperoni slices on a bed of rich marinara sauce. | bitegrill.com

This Keto Pepperoni Pizza Chicken Bake is a testament to the fact that you don't have to sacrifice flavor while eating healthy. With its simple preparation and bold, classic tastes, it is bound to become a regular rotation in your weekly meal plan.

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Recipe FAQ

Can I use chicken thighs instead of breasts?

Yes, boneless skinless chicken thighs work beautifully and often stay juicier due to their higher fat content. Adjust cooking time to 25-30 minutes, ensuring the internal temperature reaches 165°F.

What marinara sauce works best for keto?

Look for sugar-free marinara brands with no added sugars or make your own by simmering crushed tomatoes with garlic, herbs, and olive oil. Always check labels for hidden carbs.

Can I make this ahead for meal prep?

Absolutely. Assemble the casserole, cover tightly, and refrigerate for up to 24 hours before baking. Alternatively, bake fully and store individual portions for 3-4 days, reheating gently to prevent drying.

How can I reduce the spiciness?

Omit the crushed red pepper flakes entirely. You can also choose mild pepperoni or swap it for diced ham, crumbled cooked bacon, or seasoned ground turkey.

What vegetables pair well with this dish?

Steamed broccoli, roasted cauliflower, or a crisp garden salad make excellent sides. You can also add sautéed mushrooms, bell peppers, or olives as additional toppings before baking.

Can I freeze this casserole?

Freeze before baking by assembling in a freezer-safe dish, wrapping well, and storing for up to 3 months. Thaw overnight in the refrigerator before baking as directed.

Keto Pepperoni Pizza Chicken Bake

Crispy pepperoni and melted mozzarella cover seasoned chicken breasts in this satisfying low-carb casserole ready in 40 minutes.

Prep duration
10 min
Cook duration
30 min
Complete duration
40 min
Created by Ethan Walker


Skill Level Easy

Heritage American

Output 4 Portions

Dietary considerations No Gluten, Reduced-Carb

Components

Chicken

01 4 boneless, skinless chicken breasts, approximately 1.5 lbs
02 1 tablespoon olive oil
03 1/2 teaspoon salt
04 1/4 teaspoon black pepper

Sauce & Cheese

01 3/4 cup sugar-free marinara sauce
02 1 1/2 cups shredded mozzarella cheese

Toppings

01 20 slices pepperoni
02 1/2 teaspoon dried Italian seasoning
03 1/4 teaspoon crushed red pepper flakes, optional
04 2 tablespoons grated Parmesan cheese

Garnish

01 2 tablespoons chopped fresh basil or parsley, optional

Method

Phase 01

Prepare Baking Dish: Preheat oven to 400°F. Lightly grease a 9x13 inch baking dish with cooking spray or oil.

Phase 02

Season Chicken: Pat chicken breasts dry with paper towels. Season both sides generously with salt and black pepper.

Phase 03

Sear Chicken: Heat olive oil in a large skillet over medium-high heat. Sear chicken breasts for 2 to 3 minutes per side until lightly golden. Remove from heat; chicken does not need to be fully cooked at this stage.

Phase 04

Arrange in Baking Dish: Transfer seared chicken breasts to the prepared baking dish in a single layer.

Phase 05

Add Marinara Sauce: Distribute marinara sauce evenly over the chicken breasts, covering the surface thoroughly.

Phase 06

Layer Mozzarella: Sprinkle shredded mozzarella cheese uniformly over the sauce-covered chicken.

Phase 07

Top with Pepperoni: Arrange pepperoni slices over the mozzarella layer, distributing evenly across the surface.

Phase 08

Season Toppings: Sprinkle Italian seasoning, red pepper flakes if desired, and Parmesan cheese over the pepperoni layer.

Phase 09

Bake: Bake uncovered for 20 to 25 minutes until chicken reaches an internal temperature of 165°F and cheese is bubbly with golden edges.

Phase 10

Rest and Serve: Remove from oven and let rest for 5 minutes. Garnish with fresh basil or parsley if desired. Serve immediately while hot.

Tools needed

  • Large skillet
  • 9x13 inch baking dish
  • Tongs
  • Sharp knife and cutting board

Allergy details

Review each ingredient for potential allergens and consult with healthcare providers if you're uncertain about sensitivities.
  • Contains dairy: mozzarella cheese and Parmesan cheese
  • Contains pork: pepperoni; substitute with turkey pepperoni if necessary

Nutritional information (each portion)

These values are provided as estimates only and shouldn't replace professional medical guidance.
  • Energy: 380
  • Fats: 21 g
  • Carbohydrates: 5 g
  • Proteins: 42 g